Raman spectroscopy - advanced optical analysis technology
Boost plant safety, ensure product quality, and optimize operations. Raman spectroscopy measures the composition and molecular structure of your samples from lab-to-process in real time.
Specs at a glance
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Laser wavelength
785 nm -
Sample interface
Temperature: probe is non-contact; operating temp: 10 to 50 °C / 50 to 122 °F
Field of application
The union between our Raman analyzers equipped with Rxn-46 bioprocess probe technology and the BioPAT® Spectro platform by Sartorius offers the market an ideal interface to high-throughput development through single-use commercial manufacturing. Our Raman bioprocessing probe technology has been adapted to fit Sartorius’s BioPAT® Spectro platform, utilizing the same probe design for Ambr® 15, Ambr® 250, & Biostat STR® bioreactors.
Cell culture: glucose, lactate, amino acids, cell density, titer, and more
Benefits
Enables faster, easier, and more robust model building via integration with Ambr® 15 and Ambr® 250
Allows high-throughput process development which supports QbD
Provides a more efficient transfer to Biostat STR® for single-use manufacturing
Offers a scale-independent interface from 15 ml in the laboratory to 2000 L in the production suite
Requires no probe cleaning, sterilization, or frequent maintenance due to non-contact sampling
Extended selection
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High-end products
- Highly functional and convenient
Technical excellence
Simplicity
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Standard products
- Reliable, robust and low-maintenance
Technical excellence
Simplicity
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Specialized products
- Designed for demanding applications
Technical excellence
Simplicity
Variable
| FLEX selections | Technical excellence | Simplicity |
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Fundamental selection Meet your basic measurement needs |
Technical excellence
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Simplicity
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Lean selection Handle your core processes easily |
Technical excellence
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Simplicity
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Extended selection Optimize your processes with innovative technologies |
Technical excellence
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Simplicity
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Xpert selection Master your most challenging applications |
Technical excellence
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Simplicity
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Success stories
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23 documents
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Technical Information (TI)
Rxn-46 Raman Spectroscopic Probe Technical Information
System design and specifications for the Raman Rxn-46 probe
EN 03/08/202214/09/2021Language:
English
Version:
03/08/2022
File size:
380.2 KB
File name:
TI01634CEN_0222.pdf
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Operating Instruction (BA)
Sonde de spectroscopie Raman Rxn-46 Manuel de mise en service
Détails de la mise en service, de la configuration
et de la maintenance de la sonde Raman Rxn‑46EN 29/10/2025Language:
French
Version:
29/10/2025
File size:
1.4 MB
File name:
BA02170CFR_0525.pdf
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Short Instruction (KA)
Rxn-46 Raman Spectroscopic Probe Brief Operating Instructions
Quick start guide for the Raman Rxn-46 probe
EN 03/08/202214/09/2021Language:
English
Version:
03/08/2022
File size:
620.6 KB
File name:
KA01550CEN_0222.pdf
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PU (Publication)
Kaiser Raman technology and Sartorius BioPAT Spectro® collaboration Q&A - Scalable, real-time bioprocess monitoring solutions
A Q&A about how our Raman spectroscopy analyzer systems
(including the Raman Rxn2 analyzer, Raman Rxn4 analyzer,
and Rxn-46 probe), powered by Kaiser Raman technology, integrates
with the Sartorius BioPAT Spectro platform (Ambr and biostat STR) for
high throughput and single use (SUB) bioprocessingin the
biopharmaceutical life science industry.Language:
English
Version:
08/12/2021
File size:
943.7 KB
File name:
PU01446CEN_0121.pdf
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PU (Publication)
Raman application guide for the life science industry - Trusted composition analysis for the life sciences
A guide to our Raman spectroscopy application notes for the
Life Science industry (featuring the Raman Rxn2 analyzer,
Raman Rxn4 analyzer, Rxn-10 probe, Rxn-20 probe, Rxn-45 probe,
Rxn-46 probe, and probe accessory optics (bIO-Optic, Raman single
use optic system / SUB, immersion optic, non-contact optic).Language:
English
Version:
19/04/2022
File size:
1.1 MB
File name:
PU01447CEN_0222.pdf
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PU (Publication)
Top must-read Biopharma 4.0 articles - Stay informed about the latest research embracing Biopharma 4.0 principles
A list of published technical articles related to Biopharma 4.0
topics with recommendations from Life Science industry experts
at Endress+Hauser.Language:
English
Version:
26/06/2025
File size:
363.4 KB
File name:
PU01611CEN_0125.pdf
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PU (Publication)
Biopharma 4.0 model graphic
Graphic illustrating the core elements of Biopharma 4.0 including
product lifecycle stages, role of PAT/QbD, and 12 key advanced
technologies for scientists and process engineers in the Life
Sciences, applicable to Raman spectroscopy systems (Raman
Rxn2, Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and
sleeve, flow cell and flow bench, Raman optic system for single
use, and Raman calibration & verification kits).Language:
English
Version:
22/05/2025
File size:
481.6 KB
File name:
PU01614CEN_0125.pdf
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PU (Publication)
Raman-Anwendungsleitfaden für die Life-Sciences-Industrie
Ein Leitfaden zu unseren Anwendungshinweisen zur
Raman-Spektroskopie für die Life-Science-Industrie
(Raman Rxn2-Analysator, Raman Rxn4-Analysator,
Rxn-10-Sonde, Rxn-20-Sonde, Rxn-45-Sonde,
Rxn-46-Sonde und Zubehör für Sondenoptiken
(blO-Optic, Raman- Single Use-Optiksystem
/ SUB, Immersionsoptik, berührungslose Optik)Language:
German
Version:
24/09/2025
File size:
1.4 MB
File name:
PU01447CDE_0222_Raman-Anwendungsleitfaden_LSI_web.pdf
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PU (Publication)
Biopharma 4.0 model graphic (full version)
Expanded version of a graphic illustrating the core elements of
Biopharma 4.0 including product lifecycle stages, role of
PAT/QbD, and 12 key advanced technologies for scientists and
process engineers in the Life Sciences, applicable to Raman
spectroscopy systems (Raman Rxn2, Raman Rxn4, Rxn-10,
Rxn-45, Rxn-46, bio multi optic and sleeve, flow cell and flow
bench, Raman optic system for single use, and Raman calibration
& verification kits).Language:
English
Version:
22/05/2025
File size:
29.1 MB
File name:
PU01613CEN_0125.pdf
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PU (Publication)
ライフサイエンスにおけるラボからプロセスまでの監視と制御 バイオプロセスの物理的・化学的特性の信頼性の高い測定
この製品リストは、ライフサイエンス業界におけるバイオプロセス
用途向けに、光学分析および液体分析の両方から提供される分析機
器をまとめたものです。含まれる製品には、Raman Rxn2アナライザ
、Raman Rxn4アナライザ、Rxn-10プローブ、バイオマルチオプティ
ックおよびバイオスリーブ、ラマンフローアセンブリ、Rxn-45プロ
ーブ、Rxn-46プローブ、シングルユース向けラマンオプティックシ
ステム、Memosens CPS61E、Memosens COS81E、OUSBT66、Memosens
CPS77E、Memosens CLS82E、OUSAF44、Memosens CPS11E、Memosens
CLS16E、TOCアナライザーCA79、Liquiline変換器プラットフォーム
、およびMemobaseソフトウェアが含まれています。Language:
Japanese
Version:
24/08/2025
File size:
1.2 MB
File name:
PU01484CJA_0224_Lab-to-Process Control in Life Sciences.pdf
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